The MRC Centre for Transplantation was established in 2007 and was recently awarded funding from the Medical Research Council for another five years until 2017. The Centre is based within King’s College London, School of Medicine, Division of Transplantation Immunology and Mucosal Biology and also includes research groups from other Divisions at King’s.
The Centre's main aim is to bring the benefits of excellent research to people by translating basic discovery into new therapeutic, diagnostic and prognostic applications.
The MRC Centre for Transplantation spans four research themes:
1. Overcoming early inflammation after transplantation using cytoprotective therapy
2. Networks that regulate tolerance and promote long term graft acceptance
3. Immune prediction and monitoring as a guide to patient care
4. Investigating the inflammatory and immune response by external imaging
Its science base cuts across liver, kidney, pancreas, bone marrow, islet, hepatocyte and stem cell transplantation, in what is one of the largest patient groups in Europe.
The Centre incorporates a training theme in research ethics and legislation via links with the Centre of Medical Law and Ethics at KCL. The MRC Centre is closely linked with the Transplant theme of the NIHR Comprehensive Biomedical Research Centre at Guy's and St Thomas' NHS Foundation Trust.
The main administrative offices for the Centre are located at Guy's Campus of King's College London and house the Centre Director, Professor Steven Sacks, Deputy Director, Professor Anthony Dorling, Centre Manager, Dr Hélène Crutzen and Centre Administrator, Ms Melanie Regan.