An aneuploid mouse strain carrying chromosome 21 with Down syndrome phenotypes. Doherty AO, Ruf S, Mulligan C, Hildreth V, Errington ML, Cooke S, Sesay A, Modino S, Hernandez D, Linehan JM, Sharpe PT, Brandner S, Bliss TVP, Henderson DJ, Nizetic D, Tybulewicz LJ, Fisher EMC. Science 2005; 309, 2033-2037